Recombinant activated factor VII in post partum haemorrhage

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Recombinant factor VIIa for life-threatening post-partum haemorrhage.

The treatment of life-threatening post-partum haemorrhage (PPH) still remains challenging, and hysterectomy may be required to control the bleeding. We present 12 cases of severe PPH treated with recombinant factor VIIa (rFVIIa). We briefly describe the causes of the haemorrhage and the medical and surgical interventions before rVIIa administration. In 11 women there was a partial or good respo...

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Post-Partum Haemorrhage.

Post-partum haemorrhage is defined as being "excessive bleeding from any part of the genital tract after the birth of a child." Some authorities make a hair-splitting definition and describe intra-partum haemorrhage when excessive bleeding occurs before the placenta has been delivered, and confine the term post-partum haemorrhage to excessive bleeding after the completion of the third stage of ...

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Management of post-partum haemorrhage.

Management of post-partum haemorrhage (PPH) involves the treatment of uterine atony, evacuation of retained placenta or placental fragments, surgery due to uterine or birth canal trauma, balloon tamponade, effective volume replacement and transfusion therapy, and occasionally, selective arterial embolization. This article aims at introducing pregnancy- and haemorrhage-induced changes in coagula...

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Successful use of recombinant activated factor VII for postoperative associated haemorrhage: a case report

BACKGROUND Coagulopathy is a major contributing factor to bleeding related mortality even after achieving adequate surgical control of the haemorrhage in trauma and surgical patients. CASE PRESENTATION A 65 years old Greek man was admitted in our ICU with critical haemorrhage following renal biopsy. Despite surgical exploration the patient continued to bleed resulting in a vicious cycle of tr...

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ژورنال

عنوان ژورنال: Nigerian Medical Journal

سال: 2013

ISSN: 0300-1652

DOI: 10.4103/0300-1652.122328